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Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy.
Kale, Ramesh R; Kale, Manoj G; Waterson, David; Raichurkar, Anandkumar; Hameed, Shahul P; Manjunatha, M R; Kishore Reddy, B K; Malolanarasimhan, Krishnan; Shinde, Vikas; Koushik, Krishna; Jena, Lalit Kumar; Menasinakai, Sreenivasaiah; Humnabadkar, Vaishali; Madhavapeddi, Prashanti; Basavarajappa, Halesha; Sharma, Sreevalli; Nandishaiah, Radha; Mahesh Kumar, K N; Ganguly, Samit; Ahuja, Vijaykamal; Gaonkar, Sheshagiri; Naveen Kumar, C N; Ogg, Derek; Boriack-Sjodin, P Ann; Sambandamurthy, Vasan K; de Sousa, Sunita M; Ghorpade, Sandeep R.
Afiliación
  • Kale RR; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Kale MG; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Waterson D; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Raichurkar A; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Hameed SP; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Manjunatha MR; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Kishore Reddy BK; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Malolanarasimhan K; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Shinde V; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Koushik K; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Jena LK; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Menasinakai S; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Humnabadkar V; Department of Biosciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Madhavapeddi P; Department of Biosciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Basavarajappa H; Department of Biosciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Sharma S; Department of Biosciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Nandishaiah R; Department of Biosciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Mahesh Kumar KN; DMPK and Animal Sciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Ganguly S; DMPK and Animal Sciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Ahuja V; DMPK and Animal Sciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Gaonkar S; DMPK and Animal Sciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Naveen Kumar CN; DMPK and Animal Sciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Ogg D; Discovery Sciences, AstraZeneca, Alderley Park, Macclesfield, UK.
  • Boriack-Sjodin PA; Biosciences, Infection iMed, AstraZeneca, Waltham, MA, USA.
  • Sambandamurthy VK; Department of Biosciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • de Sousa SM; Department of Biosciences, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India.
  • Ghorpade SR; Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Bellary Road, Hebbal, Bangalore 560024, India. Electronic address: Sandeep.ghorpade@astrazeneca.com.
Bioorg Med Chem Lett ; 24(3): 870-9, 2014 Feb 01.
Article en En | MEDLINE | ID: mdl-24405701
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridonas / Tiazoles / Urea / Inhibidores de Topoisomerasa II / Mycobacterium tuberculosis Límite: Animals Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article País de afiliación: India
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piridonas / Tiazoles / Urea / Inhibidores de Topoisomerasa II / Mycobacterium tuberculosis Límite: Animals Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article País de afiliación: India