Synthesis and cytotoxic activities of a series of novel N-methyl-bisindolylmaleimide amide derivatives.
J Asian Nat Prod Res
; 16(3): 296-303, 2014.
Article
en En
| MEDLINE
| ID: mdl-24456252
ABSTRACT
A novel series of N-methyl-bisindolylmaleimides were synthesized and evaluated for their inhibitory activities against nine tumor cell lines. Some of the compounds showed an interesting activity against the tested cell lines. The most potent compounds 5e and 5j displayed antiproliferative activity with 50% inhibitory concentration values in the µM range against some tested cell lines.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Indoles
/
Maleimidas
/
Antineoplásicos
Límite:
Humans
Idioma:
En
Revista:
J Asian Nat Prod Res
Asunto de la revista:
BOTANICA
/
QUIMICA
Año:
2014
Tipo del documento:
Article
País de afiliación:
China