The effects of umbilical cord milking on hemodynamics and neonatal outcomes in premature neonates.
J Pediatr
; 164(5): 1045-1050.e1, 2014 May.
Article
en En
| MEDLINE
| ID: mdl-24560179
ABSTRACT
OBJECTIVE:
To determine whether umbilical cord milking (UCM) improves systemic blood flow and reduces neonatal morbidities compared with immediate cord clamping (ICC). STUDYDESIGN:
Women admitted to a tertiary care center and delivering before 32 weeks' gestation were randomized to receive UCM or ICC. Three blinded serial echocardiograms were performed in the first 2 days of the infant's life. The primary outcome was measured systemic blood flow (superior vena cava flow) at each time point.RESULTS:
Of the 60 neonates who were enrolled and randomized, 30 were assigned to cord milking and 30 to ICC. Neonates randomized to cord milking had greater measures of superior vena cava flow and right ventricular output in the first 6 hours and 30 hours of life. Neonates receiving UCM also had greater serum hemoglobin, received fewer blood transfusions, fewer days on oxygen therapy, and less frequent use of oxygen at 36 weeks' corrected postmenstrual age.CONCLUSIONS:
We demonstrate greater systemic blood flow with UCM in preterm neonates compared with ICC. Future large prospective trials are needed to determine whether UCM reduces intraventricular hemorrhage and other long-term morbidities.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Cordón Umbilical
/
Vena Cava Superior
/
Recien Nacido Prematuro
/
Atención Perinatal
Tipo de estudio:
Clinical_trials
/
Observational_studies
Límite:
Female
/
Humans
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Male
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Newborn
Idioma:
En
Revista:
J Pediatr
Año:
2014
Tipo del documento:
Article