Assessment of local structural disorders of the bladder wall in partial bladder outlet obstruction using polarized light imaging.
Biomed Opt Express
; 5(2): 621-9, 2014 Feb 01.
Article
en En
| MEDLINE
| ID: mdl-24575354
ABSTRACT
Partial bladder outlet obstruction causes prominent morphological changes in the bladder wall, which leads to bladder dysfunction. In this paper, we demonstrate that polarized light imaging can be used to identify the location of obstruction induced structural changes that other imaging modalities fail to detect. We induced 2-week and 6-week partial outlet obstruction in rats, harvested obstructed bladders, then measured their retardances while distended to high pressures and compared them to controls. Our results show that the retardance of the central part of the ventral side (above the ureters) closer to the urethra can be used as a potential metric of the distending bladder obstruction.
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Biomed Opt Express
Año:
2014
Tipo del documento:
Article