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Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release.
Ilyinskii, Petr O; Roy, Christopher J; O'Neil, Conlin P; Browning, Erica A; Pittet, Lynnelle A; Altreuter, David H; Alexis, Frank; Tonti, Elena; Shi, Jinjun; Basto, Pamela A; Iannacone, Matteo; Radovic-Moreno, Aleksandar F; Langer, Robert S; Farokhzad, Omid C; von Andrian, Ulrich H; Johnston, Lloyd P M; Kishimoto, Takashi Kei.
Afiliación
  • Ilyinskii PO; Selecta Biosciences, Watertown, MA 02472, USA. Electronic address: PIlyinskii@selectabio.com.
  • Roy CJ; Selecta Biosciences, Watertown, MA 02472, USA.
  • O'Neil CP; Selecta Biosciences, Watertown, MA 02472, USA.
  • Browning EA; Selecta Biosciences, Watertown, MA 02472, USA.
  • Pittet LA; Selecta Biosciences, Watertown, MA 02472, USA.
  • Altreuter DH; Selecta Biosciences, Watertown, MA 02472, USA.
  • Alexis F; Laboratory of Nanomedicine and Biomaterials, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Tonti E; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Shi J; Laboratory of Nanomedicine and Biomaterials, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Basto PA; David H. Koch Institute for Integrative Cancer Research, Cambridge, MA 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA.
  • Iannacone M; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Radovic-Moreno AF; David H. Koch Institute for Integrative Cancer Research, Cambridge, MA 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA.
  • Langer RS; David H. Koch Institute for Integrative Cancer Research, Cambridge, MA 02139, USA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA.
  • Farokhzad OC; Laboratory of Nanomedicine and Biomaterials, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • von Andrian UH; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Johnston LP; Selecta Biosciences, Watertown, MA 02472, USA.
  • Kishimoto TK; Selecta Biosciences, Watertown, MA 02472, USA.
Vaccine ; 32(24): 2882-95, 2014 May 19.
Article en En | MEDLINE | ID: mdl-24593999
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas Sintéticas / Adyuvantes Inmunológicos / Nanopartículas Límite: Animals Idioma: En Revista: Vaccine Año: 2014 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas Sintéticas / Adyuvantes Inmunológicos / Nanopartículas Límite: Animals Idioma: En Revista: Vaccine Año: 2014 Tipo del documento: Article