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Higher body mass index in adults at diagnosis of the slowly progressive form of type 1 diabetes mellitus is associated with lower risk HLA genes.
Fourlanos, S; Elkassaby, S; Varney, M D; Colman, P G; Harrison, L C.
Afiliación
  • Fourlanos S; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3052, VIC; Department of Diabetes and Endocrinology, The Royal Melbourne Hospital, Parkville 3050, VIC, Australia.
  • Elkassaby S; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3052, VIC; Department of Diabetes and Endocrinology, The Royal Melbourne Hospital, Parkville 3050, VIC, Australia.
  • Varney MD; Victorian Transplantation and Immunogenetics Service, Australian Red Cross Blood Service, West Melbourne 3003, VIC, Australia.
  • Colman PG; Department of Diabetes and Endocrinology, The Royal Melbourne Hospital, Parkville 3050, VIC, Australia.
  • Harrison LC; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3052, VIC. Electronic address: harrison@wehi.edu.
Diabetes Res Clin Pract ; 104(3): e69-71, 2014 Jun.
Article en En | MEDLINE | ID: mdl-24698405
ABSTRACT
We hypothesised that higher body weight, a proposed risk factor for type 1 diabetes mellitus, would be associated with increased penetrance of lower risk genes. In adults at diagnosis of the slowly progressive form of type 1 diabetes mellitus we found that higher body mass index was associated with the absence of the highest risk HLA genes.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Antígenos HLA-DQ / Antígenos HLA-DR / Índice de Masa Corporal / Diabetes Mellitus Tipo 1 Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Res Clin Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Australia
Texto completo
Imprimir
XML
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Antígenos HLA-DQ / Antígenos HLA-DR / Índice de Masa Corporal / Diabetes Mellitus Tipo 1 Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Res Clin Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Australia