Critical role for NAD glycohydrolase in regulation of erythropoiesis by hematopoietic stem cells through control of intracellular NAD content.

Nam, Tae-Sik; Park, Kwang-Hyun; Shawl, Asif Iqbal; Kim, Byung-Ju; Han, Myung-Kwan; Kim, Youngho; Moss, Joel; Kim, Uh-Hyun

Nam, Tae-Sik; Park, Kwang-Hyun; Shawl, Asif Iqbal; Kim, Byung-Ju; Han, Myung-Kwan; Kim, Youngho; Moss, Joel; Kim, Uh-Hyun.

Afiliación

Nam TS; From the Department of Biochemistry, National Creative Research Laboratory for Ca Signaling Network, and.
Park KH; From the Department of Biochemistry, National Creative Research Laboratory for Ca Signaling Network, and.
Shawl AI; From the Department of Biochemistry, National Creative Research Laboratory for Ca Signaling Network, and.
Kim BJ; From the Department of Biochemistry, National Creative Research Laboratory for Ca Signaling Network, and.
Han MK; Department of Microbiology, Chonbuk National University Medical School, Jeonju 561-182, Korea.
Kim Y; Department of Biochemistry, School of Medicine, Wonkwang University, Iksan 570-749, Korea, and.
Moss J; Cardiovascular and Pulmonary Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892.
Kim UH; From the Department of Biochemistry, National Creative Research Laboratory for Ca Signaling Network, and Institute of Cardiovascular Research, Chonbuk National University Medical School, Jeonju 561-182, Korea, uhkim@chonbuk.ac.kr.

J Biol Chem ; 289(23): 16362-73, 2014 Jun 06.

Article en En | MEDLINE | ID: mdl-24759100

Asunto(s)

Eritropoyesis; Células Madre Hematopoyéticas/metabolismo; NAD+ Nucleosidasa/metabolismo; NAD/metabolismo; Secuencia de Aminoácidos; Animales; Secuencia de Bases; Western Blotting; ADN Complementario; Glicosilación; Células HEK293; Humanos; Microscopía Confocal; Datos de Secuencia Molecular; Mutagénesis Sitio-Dirigida; NAD+ Nucleosidasa/química; NAD+ Nucleosidasa/genética; Conejos; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Relación Estructura-Actividad

Palabras clave

CD38; Erythrocyte; Erythropoiesis; Hematopoietic Stem Cell; Intracellular NAD; NAD Glycohydrolase; Nicotinamide; Nicotinamide Adenine Dinucleotide (NAD); Reticulocytes

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Hematopoyéticas / NAD/ Nucleosidasa / Eritropoyesis / NAD Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

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