Special deLIVERy: podocyte injury promotes renal angiotensin II generation from liver-derived angiotensinogen.
Kidney Int
; 85(5): 1009-11, 2014 May.
Article
en En
| MEDLINE
| ID: mdl-24786873
ABSTRACT
The role of the circulating renin-angiotensin system (RAS) in regulating systemic blood pressure and sodium balance is well established. More recently, researchers have turned their focus to the local generation of angiotensin II (Ang II) in specific tissues. Matsusaka et al. revisit the renal RAS and provide evidence that liver-derived angiotensinogen (AGT) is a major determinant of renal Ang II levels in a model of podocyte injury.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Angiotensina II
/
Angiotensinógeno
/
Podocitos
/
Enfermedades Renales
/
Túbulos Renales Proximales
/
Hígado
Límite:
Animals
Idioma:
En
Revista:
Kidney Int
Año:
2014
Tipo del documento:
Article
País de afiliación:
Estados Unidos