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Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein.
Karaca, Ilker; Tamboli, Irfan Y; Glebov, Konstantin; Richter, Josefine; Fell, Lisa H; Grimm, Marcus O; Haupenthal, Viola J; Hartmann, Tobias; Gräler, Markus H; van Echten-Deckert, Gerhild; Walter, Jochen.
Afiliación
  • Karaca I; From the Department of Neurology, University of Bonn, 53127 Bonn, Germany.
  • Tamboli IY; From the Department of Neurology, University of Bonn, 53127 Bonn, Germany.
  • Glebov K; From the Department of Neurology, University of Bonn, 53127 Bonn, Germany.
  • Richter J; German Center for Neurodegenerative Diseases (DZNE), 53175 Bonn, Germany.
  • Fell LH; the Department of Experimental Neurology, University of the Saarland, 66421 Homburg/Saar, Germany.
  • Grimm MO; the Department of Experimental Neurology, University of the Saarland, 66421 Homburg/Saar, Germany.
  • Haupenthal VJ; the Department of Experimental Neurology, University of the Saarland, 66421 Homburg/Saar, Germany.
  • Hartmann T; the Department of Experimental Neurology, University of the Saarland, 66421 Homburg/Saar, Germany.
  • Gräler MH; the Department of Anaesthesiology and Intensive Care Medicine, Center for Sepsis Control and Care, and Center for Molecular Biomedicine, University Hospital Jena, 07740 Jena, Germany, and.
  • van Echten-Deckert G; the Life and Medical Sciences, Membrane Biology and Lipid Biochemistry Unit at the Kekulé-Institute, University of Bonn, 53121 Bonn, Germany.
  • Walter J; From the Department of Neurology, University of Bonn, 53127 Bonn, Germany, Jochen.Walter@ukb.uni-bonn.de.
J Biol Chem ; 289(24): 16761-72, 2014 Jun 13.
Article en En | MEDLINE | ID: mdl-24808180

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Precursor de Proteína beta-Amiloide / Aldehído-Liasas / Lisosomas Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Precursor de Proteína beta-Amiloide / Aldehído-Liasas / Lisosomas Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article País de afiliación: Alemania