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KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission.
Kuhen, Kelli L; Chatterjee, Arnab K; Rottmann, Matthias; Gagaring, Kerstin; Borboa, Rachel; Buenviaje, Jennifer; Chen, Zhong; Francek, Carolyn; Wu, Tao; Nagle, Advait; Barnes, S Whitney; Plouffe, David; Lee, Marcus C S; Fidock, David A; Graumans, Wouter; van de Vegte-Bolmer, Marga; van Gemert, Geert J; Wirjanata, Grennady; Sebayang, Boni; Marfurt, Jutta; Russell, Bruce; Suwanarusk, Rossarin; Price, Ric N; Nosten, Francois; Tungtaeng, Anchalee; Gettayacamin, Montip; Sattabongkot, Jetsumon; Taylor, Jennifer; Walker, John R; Tully, David; Patra, Kailash P; Flannery, Erika L; Vinetz, Joseph M; Renia, Laurent; Sauerwein, Robert W; Winzeler, Elizabeth A; Glynne, Richard J; Diagana, Thierry T.
Afiliación
  • Kuhen KL; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Chatterjee AK; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Rottmann M; Swiss Tropical and Public Health Institute, Parasite Chemotherapy, Basel, Switzerland University of Basel, Basel, Switzerland.
  • Gagaring K; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Borboa R; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Buenviaje J; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Chen Z; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Francek C; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Wu T; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Nagle A; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Barnes SW; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Plouffe D; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Lee MC; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, New York, USA.
  • Fidock DA; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, New York, USA Division of Infectious Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.
  • Graumans W; Radboud University Nijmegen Medical Center, Medical Microbiology Department, Nijmegen, The Netherlands.
  • van de Vegte-Bolmer M; Radboud University Nijmegen Medical Center, Medical Microbiology Department, Nijmegen, The Netherlands.
  • van Gemert GJ; Radboud University Nijmegen Medical Center, Medical Microbiology Department, Nijmegen, The Netherlands.
  • Wirjanata G; Global Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
  • Sebayang B; Eijkman Institute for Molecular Biology, Jakarta, Indonesia.
  • Marfurt J; Global Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
  • Russell B; Laboratory of Malaria Immunobiology, Singapore Immunology Network, Agency for Science Technology and Research, Biopolis, Singapore.
  • Suwanarusk R; Laboratory of Malaria Immunobiology, Singapore Immunology Network, Agency for Science Technology and Research, Biopolis, Singapore.
  • Price RN; Global Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Australia Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
  • Nosten F; Shoklo Malaria Research Unit, Mae Sot, Tak, Thailand Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
  • Tungtaeng A; Department of Veterinary Medicine, U.S. Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
  • Gettayacamin M; Department of Veterinary Medicine, U.S. Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
  • Sattabongkot J; Entomology Department, AFRIMS, Bangkok, Thailand Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
  • Taylor J; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Walker JR; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Tully D; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Patra KP; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, California, USA.
  • Flannery EL; Division of Pharmacology and Drug Discovery, University of California, San Diego, School of Medicine, La Jolla, California, USA.
  • Vinetz JM; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, California, USA.
  • Renia L; Laboratory of Malaria Immunobiology, Singapore Immunology Network, Agency for Science Technology and Research, Biopolis, Singapore.
  • Sauerwein RW; Radboud University Nijmegen Medical Center, Medical Microbiology Department, Nijmegen, The Netherlands.
  • Winzeler EA; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA Division of Pharmacology and Drug Discovery, University of California, San Diego, School of Medicine, La Jolla, California, USA.
  • Glynne RJ; Genomics Institute of the Novartis Research Foundation, San Diego, California, USA.
  • Diagana TT; Novartis Institute for Tropical Diseases, Singapore thierry.diagana@novartis.com.
Antimicrob Agents Chemother ; 58(9): 5060-7, 2014 Sep.
Article en En | MEDLINE | ID: mdl-24913172
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Malaria Falciparum / Imidazoles / Antimaláricos Límite: Animals Idioma: En Revista: Antimicrob Agents Chemother Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Malaria Falciparum / Imidazoles / Antimaláricos Límite: Animals Idioma: En Revista: Antimicrob Agents Chemother Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos