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A rat toxicogenomics study with the calcium sensitizer EMD82571 reveals a pleiotropic cause of teratogenicity.
Hewitt, Philip G; Singh, Prafull Kumar; Kumar, Arun; Gnewuch, Carsten; Liebisch, Gerhard; Schmitz, Gerd; Borlak, Juergen.
Afiliación
  • Hewitt PG; Non-Clinical Safety, Merck Serono, 64283 Darmstadt, Germany. Electronic address: philip.hewitt@merckgroup.com.
  • Singh PK; Centre for Pharmacology and Toxicology, Hannover Medical School, 30625 Hannover, Germany. Electronic address: Singh.Prafull@mh-hannover.de.
  • Kumar A; Centre for Pharmacology and Toxicology, Hannover Medical School, 30625 Hannover, Germany. Electronic address: Kumar.Arun@mh-hannover.de.
  • Gnewuch C; Institute for Clinical Chemistry and Laboratory Medicine, Regensburg University Medical Center, 93053 Regensburg, Germany. Electronic address: carsten.gnewuch@ukr.de.
  • Liebisch G; Institute for Clinical Chemistry and Laboratory Medicine, Regensburg University Medical Center, 93053 Regensburg, Germany. Electronic address: gerhard.liebisch@ukr.de.
  • Schmitz G; Institute for Clinical Chemistry and Laboratory Medicine, Regensburg University Medical Center, 93053 Regensburg, Germany. Electronic address: gerd.schmitz@ukr.de.
  • Borlak J; Centre for Pharmacology and Toxicology, Hannover Medical School, 30625 Hannover, Germany. Electronic address: Borlak.Juergen@mh-hannover.de.
Reprod Toxicol ; 47: 89-101, 2014 Aug.
Article en En | MEDLINE | ID: mdl-24977338
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinolinas / Teratógenos / Tiadiazinas / Inhibidores de Fosfodiesterasa 3 Límite: Animals / Pregnancy Idioma: En Revista: Reprod Toxicol Asunto de la revista: EMBRIOLOGIA / MEDICINA REPRODUTIVA / TOXICOLOGIA Año: 2014 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinolinas / Teratógenos / Tiadiazinas / Inhibidores de Fosfodiesterasa 3 Límite: Animals / Pregnancy Idioma: En Revista: Reprod Toxicol Asunto de la revista: EMBRIOLOGIA / MEDICINA REPRODUTIVA / TOXICOLOGIA Año: 2014 Tipo del documento: Article