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Fcγ receptor dependency of agonistic CD40 antibody in lymphoma therapy can be overcome through antibody multimerization.
White, Ann L; Dou, Lang; Chan, H T Claude; Field, Vikki L; Mockridge, C Ian; Moss, Kane; Williams, Emily L; Booth, Steven G; French, Ruth R; Potter, Elizabeth A; Butts, Cherié; Al-Shamkhani, Aymen; Cragg, Mark S; Verbeek, J Sjef; Johnson, Peter W M; Glennie, Martin J; Beers, Stephen A.
Afiliación
  • White AL; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Dou L; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Chan HT; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Field VL; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Mockridge CI; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Moss K; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Williams EL; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Booth SG; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • French RR; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Potter EA; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Butts C; Immunology Research, Biogen Idec, Cambridge, MA 02142;
  • Al-Shamkhani A; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Cragg MS; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Verbeek JS; Department of Human Genetics, Leiden University Medical Centre, 2333 ZA Leiden, the Netherlands; and.
  • Johnson PW; Cancer Sciences Unit, Southampton Cancer Research UK Centre, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom.
  • Glennie MJ; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom;
  • Beers SA; Antibody and Vaccine Group, Cancer Sciences Unit, University of Southampton Faculty of Medicine, Southampton SO16 6YD, United Kingdom; sab@soton.ac.uk.
J Immunol ; 193(4): 1828-35, 2014 Aug 15.
Article en En | MEDLINE | ID: mdl-25024386

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de IgG / Antígenos CD40 / Multimerización de Proteína / Linfoma / Anticuerpos Monoclonales Límite: Animals Idioma: En Revista: J Immunol Año: 2014 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de IgG / Antígenos CD40 / Multimerización de Proteína / Linfoma / Anticuerpos Monoclonales Límite: Animals Idioma: En Revista: J Immunol Año: 2014 Tipo del documento: Article