Neuronal cell-surface protein neurexin 1 interaction with multi-PDZ domain protein MUPP1.
Biosci Biotechnol Biochem
; 78(4): 644-6, 2014.
Article
en En
| MEDLINE
| ID: mdl-25036961
ABSTRACT
Location of membrane proteins is often stabilized by PDZ domain-containing scaffolding proteins. Using the yeast two-hybrid screening, we found that neurexin 1 interacted with multi-PDZ domain protein 1 (MUPP1) through PDZ domain. Neurexin 2 and 3 also interacted with MUPP1. MUPP1 and neurexin 1 were co-localized in cultured cells. These results suggest a novel mechanism for localizing neurexin 1 to synaptic sites.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Proteínas Portadoras
/
Moléculas de Adhesión de Célula Nerviosa
/
Dominios PDZ
/
Neuronas
Límite:
Animals
Idioma:
En
Revista:
Biosci Biotechnol Biochem
Asunto de la revista:
BIOQUIMICA
/
BIOTECNOLOGIA
Año:
2014
Tipo del documento:
Article