Magnetomotive optical coherence elastography using magnetic particles to induce mechanical waves.
Biomed Opt Express
; 5(7): 2349-61, 2014 Jul 01.
Article
en En
| MEDLINE
| ID: mdl-25071969
ABSTRACT
Magnetic particles are versatile imaging agents that have found wide spread applicability in diagnostic, therapeutic, and rheology applications. In this study, we demonstrate that mechanical waves generated by a localized inclusion of magnetic nanoparticles can be used for assessment of the tissue viscoelastic properties using magnetomotive optical coherence elastography. We show these capabilities in tissue mimicking elastic and viscoelastic phantoms and in biological tissues by measuring the shear wave speed under magnetomotive excitation. Furthermore, we demonstrate the extraction of the complex shear modulus by measuring the shear wave speed at different frequencies and fitting to a Kelvin-Voigt model.
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Biomed Opt Express
Año:
2014
Tipo del documento:
Article
País de afiliación:
Estados Unidos