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RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.
Wolfe, Andrew L; Singh, Kamini; Zhong, Yi; Drewe, Philipp; Rajasekhar, Vinagolu K; Sanghvi, Viraj R; Mavrakis, Konstantinos J; Jiang, Man; Roderick, Justine E; Van der Meulen, Joni; Schatz, Jonathan H; Rodrigo, Christina M; Zhao, Chunying; Rondou, Pieter; de Stanchina, Elisa; Teruya-Feldstein, Julie; Kelliher, Michelle A; Speleman, Frank; Porco, John A; Pelletier, Jerry; Rätsch, Gunnar; Wendel, Hans-Guido.
Afiliación
  • Wolfe AL; 1] Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Weill Cornell Graduate School of Medical Sciences, New York, New York 10065, USA [3].
  • Singh K; 1] Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2].
  • Zhong Y; Computational Biology Department, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Drewe P; Computational Biology Department, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Rajasekhar VK; Stem Cell Center and Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Sanghvi VR; Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Mavrakis KJ; 1] Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Novartis, Cambridge, Massachusetts 02139, USA (K.J.M.); The University of Arizona Cancer Center, Tucson, Arizona 85719, USA (J.H.S.).
  • Jiang M; Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Roderick JE; Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605 USA.
  • Van der Meulen J; 1] Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.
  • Schatz JH; 1] Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [3] Novartis, Cambridge, Massachusetts 02139, USA (K.J.M.); The University of Arizona Cancer Center,
  • Rodrigo CM; Department of Chemistry, Center for Chemical Methodology and Library Development, Boston University, Boston, Massachusetts 02215, USA.
  • Zhao C; Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Rondou P; Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.
  • de Stanchina E; Molecular Pharmacology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Teruya-Feldstein J; Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Kelliher MA; Department of Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605 USA.
  • Speleman F; Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.
  • Porco JA; Department of Chemistry, Center for Chemical Methodology and Library Development, Boston University, Boston, Massachusetts 02215, USA.
  • Pelletier J; 1] Department of Biochemistry, McGill University, Montreal, Quebec H3G 1Y6, Canada [2] Department of Oncology, McGill University, Montreal, Quebec H3G 1Y6, Canada [3] The Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, Quebec H3G 1Y6, Canada.
  • Rätsch G; Computational Biology Department, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
  • Wendel HG; Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
Nature ; 513(7516): 65-70, 2014 Sep 04.
Article en En | MEDLINE | ID: mdl-25079319
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biosíntesis de Proteínas / Proteínas Oncogénicas / Regiones no Traducidas 5' / Factor 4A Eucariótico de Iniciación / Leucemia-Linfoma Linfoblástico de Células T Precursoras / G-Cuádruplex Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biosíntesis de Proteínas / Proteínas Oncogénicas / Regiones no Traducidas 5' / Factor 4A Eucariótico de Iniciación / Leucemia-Linfoma Linfoblástico de Células T Precursoras / G-Cuádruplex Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article