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Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning.
Saez, Borja; Ferraro, Francesca; Yusuf, Rushdia Z; Cook, Colleen M; Yu, Vionnie W C; Pardo-Saganta, Ana; Sykes, Stephen M; Palchaudhuri, Rahul; Schajnovitz, Amir; Lotinun, Sutada; Lymperi, Stefania; Mendez-Ferrer, Simon; Toro, Raquel Del; Day, Robyn; Vasic, Radovan; Acharya, Sanket S; Baron, Roland; Lin, Charles P; Yamaguchi, Yu; Wagers, Amy J; Scadden, David T.
Afiliación
  • Saez B; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
  • Ferraro F; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
  • Yusuf RZ; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
  • Cook CM; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
  • Yu VW; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
  • Pardo-Saganta A; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
  • Sykes SM; Immune Cell Development and Host Defense, Research Institute of Fox Chase Cancer Center, Philadelphia, PA;
  • Palchaudhuri R; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
  • Schajnovitz A; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
  • Lotinun S; Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, MA;
  • Lymperi S; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
  • Mendez-Ferrer S; Cardiovascular Development and Repair, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain;
  • Toro RD; Cardiovascular Development and Repair, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain;
  • Day R; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA;
  • Vasic R; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA;
  • Acharya SS; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA;
  • Baron R; Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, MA;
  • Lin CP; Harvard Stem Cell Institute, Cambridge, MA; Advanced Microscopy Program, Wellman Center for Photomedicine and Center for Systems Biology, Massachusetts General Hospital, Boston, MA;
  • Yamaguchi Y; Sanford-Burnham Medical Research Institute, La Jolla, CA;
  • Wagers AJ; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Harvard Stem Cell Institute, Cambridge, MA; Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA; and Howard Hughes Medical Institute, Cambridge, MA.
  • Scadden DT; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; Harvard Stem Cell Institute, Cambridge, MA;
Blood ; 124(19): 2937-47, 2014 Nov 06.
Article en En | MEDLINE | ID: mdl-25202142
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células del Estroma / N-Acetilglucosaminiltransferasas / Trasplante de Células Madre Hematopoyéticas / Acondicionamiento Pretrasplante / Movilización de Célula Madre Hematopoyética / Heparitina Sulfato Límite: Animals Idioma: En Revista: Blood Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células del Estroma / N-Acetilglucosaminiltransferasas / Trasplante de Células Madre Hematopoyéticas / Acondicionamiento Pretrasplante / Movilización de Célula Madre Hematopoyética / Heparitina Sulfato Límite: Animals Idioma: En Revista: Blood Año: 2014 Tipo del documento: Article