Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy.

Yang, Andrew I; Khawaja, Ayaz M; Ballester-Fuentes, Leo; Pack, Svetlana D; Abdullaev, Ziedulla; Patronas, Nicholas J; Inati, Sara K; Theodore, William H; Quezado, Martha M; Zaghloul, Kareem A

Yang, Andrew I; Khawaja, Ayaz M; Ballester-Fuentes, Leo; Pack, Svetlana D; Abdullaev, Ziedulla; Patronas, Nicholas J; Inati, Sara K; Theodore, William H; Quezado, Martha M; Zaghloul, Kareem A.

Afiliación

Yang AI; Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda.
Khawaja AM; Department of Neurology, University of Alabama at Birmingham, Birmingham.
Ballester-Fuentes L; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda.
Pack SD; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda.
Abdullaev Z; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda.
Patronas NJ; Section of Neuroradiology, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda.
Inati SK; EEG Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda.
Theodore WH; Clinical Epilepsy Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Quezado MM; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda.
Zaghloul KA; Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda.

Epileptic Disord ; 16(3): 328-32, 2014 Sep.

Article en En | MEDLINE | ID: mdl-25204011

ABSTRACT

ABSTRACT

Dysembryoplastic neuroepithelial tumours (DNET) are a common cause of tumour-associated epilepsy, and are usually located in the temporal lobes. We present a case of multifocal DNETs in both infra- and supra-tentorial locations, in a 23-year-old man with a coincident Type I Chiari malformation, presenting with medically refractory focal seizures. The extensive anatomical distribution of the lesions suggests a genetic component in their tumourigenesis.

Asunto(s)

Neoplasias Encefálicas/complicaciones; Epilepsia/etiología; Neoplasias Neuroepiteliales/complicaciones; Convulsiones/etiología; Lóbulo Temporal/patología; Neoplasias Encefálicas/patología; Epilepsia/patología; Humanos; Masculino; Neoplasias Neuroepiteliales/patología; Convulsiones/patología; Adulto Joven

Palabras clave

Chiari malformation; multi-focal tumor; tumor-associated epilepsy

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Convulsiones / Lóbulo Temporal / Neoplasias Encefálicas / Neoplasias Neuroepiteliales / Epilepsia Tipo de estudio: Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: Epileptic Disord Asunto de la revista: CEREBRO / NEUROLOGIA Año: 2014 Tipo del documento: Article

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