Post-translational regulation of mitogen-activated protein kinase phosphatase (MKP)-1 and MKP-2 in macrophages following lipopolysaccharide stimulation: the role of the C termini of the phosphatases in determining their stability.

Crowell, Sara; Wancket, Lyn M; Shakibi, Yasmine; Xu, Pingping; Xue, Jianjing; Samavati, Lobelia; Nelin, Leif D; Liu, Yusen

Crowell, Sara; Wancket, Lyn M; Shakibi, Yasmine; Xu, Pingping; Xue, Jianjing; Samavati, Lobelia; Nelin, Leif D; Liu, Yusen.

Afiliación

Crowell S; From the Center for Perinatal Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205.
Wancket LM; Department of Veterinary Bioscience, The Ohio State University College of Veterinary Medicine, Columbus, Ohio 43210, and.
Shakibi Y; From the Center for Perinatal Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205.
Xu P; From the Center for Perinatal Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205.
Xue J; From the Center for Perinatal Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205.
Samavati L; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University School of Medicine and Detroit Medical Center, Detroit, Michigan 48201.
Nelin LD; From the Center for Perinatal Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43205.
Liu Y; From the Center for Perinatal Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio 43205, Department of Veterinary Bioscience, The Ohio State University College of Veterinary Medicine, Columbus, Ohio 43210, and Department of Pediatrics, The Ohio State University College

J Biol Chem ; 289(42): 28753-64, 2014 Oct 17.

Article en En | MEDLINE | ID: mdl-25204653

Asunto(s)

Fosfatasa 1 de Especificidad Dual/metabolismo; Fosfatasas de Especificidad Dual/metabolismo; Macrófagos/enzimología; Fosfatasas de la Proteína Quinasa Activada por Mitógenos/metabolismo; Procesamiento Proteico-Postraduccional; Proteínas Tirosina Fosfatasas/metabolismo; Alanina/química; Animales; Epítopos/metabolismo; Regulación Enzimológica de la Expresión Génica; Células HEK293; Humanos; Lipopolisacáridos/química; Ratones; Fosforilación; Inhibidores de Proteasoma/química; Conformación Proteica; Estructura Terciaria de Proteína; Ubiquitina/metabolismo; Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo

Palabras clave

Lipopolysaccharide (LPS); MAP Kinase Phosphatase; Macrophage; Phosphorylation; Post-translational Modification (PTM); Protein Stability; Ubiquitylation (Ubiquitination)

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Procesamiento Proteico-Postraduccional / Proteínas Tirosina Fosfatasas / Fosfatasas de la Proteína Quinasa Activada por Mitógenos / Fosfatasa 1 de Especificidad Dual / Fosfatasas de Especificidad Dual / Macrófagos Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google