Blood sampling via a peripheral artery catheter decreases cerebral oxygenation index in very low-birthweight infants.
Acta Paediatr
; 103(12): 1227-32, 2014 Dec.
Article
en En
| MEDLINE
| ID: mdl-25220877
ABSTRACT
AIM:
This study evaluated the impact of blood sampling via peripheral arterial catheters on cerebral oxygenation and blood volume as a function of blood sampling velocity.METHODS:
Near-infrared spectroscopy was applied to 20 very low-birthweight infants during peripheral arterial blood sampling. Changes in cerebral oxygenated, deoxygenated and total haemoglobin, cerebral blood volume and cerebral oxygenation index were recorded. Heart rate and oxygen saturation were measured continuously. To assess the impact of blood sampling velocity, both fast 40-sec and slow 70-sec sampling procedures were performed in a crossover study design, in which the order of sampling velocities was randomised for each patient.RESULTS:
Both fast and slow blood sampling procedures resulted in a significant decrease in cerebral oxygenation index (fast, p = 0.002, slow, p = 0.008), and an increase in mean heart rate (both p = 0.02) and mean blood pressure (p = 0.02 and 0.04). Oxygenated and total haemoglobin and cerebral blood volume only decreased significantly after slow blood sampling (p < 0.001).CONCLUSION:
Blood sampling from peripheral arterial catheters leads to significant fluctuations in cerebral oxygenation independent of the sampling velocity. Changes are comparable to those reported from umbilical blood sampling. We advise that blood sampling should be restricted as much as possible.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Oxígeno
/
Encéfalo
/
Cateterismo Periférico
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Recolección de Muestras de Sangre
/
Enfermedades del Prematuro
Tipo de estudio:
Clinical_trials
Límite:
Female
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Humans
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Male
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Newborn
Idioma:
En
Revista:
Acta Paediatr
Año:
2014
Tipo del documento:
Article
País de afiliación:
Alemania