[Pheochromocytoma and paraganglioma: basics for the general practitioner]. / Phéochromocytome et paragangliome: que doit retenir le praticien?
Rev Med Suisse
; 10(441): 1650-2, 1654-5, 2014 Sep 10.
Article
en Fr
| MEDLINE
| ID: mdl-25322623
ABSTRACT
Pheochromocytomas (PHEO) and paragangliomas (PGL) are rare neuroendocrine tumors secreting catecholamines in most cases. The clinic can be very variable. Morbidity and mortality PHEO and PGL are primarily cardiovascular and haves catecholamine-mediated origin. The PHEO and PGL can sign in with a syndromic association with multiple tumors and genetic counseling is necessary in search of a germline mutation. The first step includes a diagnostic assay of metanephrine and normetanephrines. In case of positive biology a CT or MRI imaging will be needed to locate the tumor. Treatment with alpha-blocker before surgery reduces the perioperative risk. A long term follow up is recommended to detect recurrence.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Paraganglioma
/
Feocromocitoma
/
Neoplasias de las Glándulas Suprarrenales
Límite:
Humans
/
Male
/
Middle aged
Idioma:
Fr
Revista:
Rev Med Suisse
Asunto de la revista:
MEDICINA
Año:
2014
Tipo del documento:
Article