First total synthesis of ganglioside DSG-A possessing neuritogenic activity.
Org Biomol Chem
; 12(46): 9345-9, 2014 Dec 14.
Article
en En
| MEDLINE
| ID: mdl-25338766
ABSTRACT
The first total synthesis of ganglioside DSG-A (1) is achieved via chemoselective glycosylation and a [1 + 1 + 2] synthetic strategy. We have also developed an efficient method that can be handled on large scale (50 g) for the synthesis of the phytosphingosine.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Esfingosina
/
Gangliósidos
Límite:
Animals
Idioma:
En
Revista:
Org Biomol Chem
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2014
Tipo del documento:
Article
País de afiliación:
Taiwán