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PD-1 blockade induces responses by inhibiting adaptive immune resistance.
Tumeh, Paul C; Harview, Christina L; Yearley, Jennifer H; Shintaku, I Peter; Taylor, Emma J M; Robert, Lidia; Chmielowski, Bartosz; Spasic, Marko; Henry, Gina; Ciobanu, Voicu; West, Alisha N; Carmona, Manuel; Kivork, Christine; Seja, Elizabeth; Cherry, Grace; Gutierrez, Antonio J; Grogan, Tristan R; Mateus, Christine; Tomasic, Gorana; Glaspy, John A; Emerson, Ryan O; Robins, Harlan; Pierce, Robert H; Elashoff, David A; Robert, Caroline; Ribas, Antoni.
Afiliación
  • Tumeh PC; 1] University of California Los Angeles (UCLA), Los Angeles, California 90095, USA [2] Jonsson Comprehensive Cancer Center, Los Angeles, California 90095, USA.
  • Harview CL; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Yearley JH; Merck &Co, Palo Alto, California 94304, USA.
  • Shintaku IP; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Taylor EJ; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Robert L; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Chmielowski B; 1] University of California Los Angeles (UCLA), Los Angeles, California 90095, USA [2] Jonsson Comprehensive Cancer Center, Los Angeles, California 90095, USA.
  • Spasic M; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Henry G; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Ciobanu V; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • West AN; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Carmona M; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Kivork C; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Seja E; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Cherry G; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Gutierrez AJ; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Grogan TR; University of California Los Angeles (UCLA), Los Angeles, California 90095, USA.
  • Mateus C; Gustave Roussy and INSERM U981, Villejuif, Paris Sud, France.
  • Tomasic G; Gustave Roussy and INSERM U981, Villejuif, Paris Sud, France.
  • Glaspy JA; 1] University of California Los Angeles (UCLA), Los Angeles, California 90095, USA [2] Jonsson Comprehensive Cancer Center, Los Angeles, California 90095, USA.
  • Emerson RO; Adaptive Biotechnologies, Seattle, Washington 98102, USA.
  • Robins H; 1] Adaptive Biotechnologies, Seattle, Washington 98102, USA [2] Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
  • Pierce RH; Merck &Co, Palo Alto, California 94304, USA.
  • Elashoff DA; 1] University of California Los Angeles (UCLA), Los Angeles, California 90095, USA [2] Jonsson Comprehensive Cancer Center, Los Angeles, California 90095, USA.
  • Robert C; Gustave Roussy and INSERM U981, Villejuif, Paris Sud, France.
  • Ribas A; 1] University of California Los Angeles (UCLA), Los Angeles, California 90095, USA [2] Jonsson Comprehensive Cancer Center, Los Angeles, California 90095, USA.
Nature ; 515(7528): 568-71, 2014 Nov 27.
Article en En | MEDLINE | ID: mdl-25428505
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Inmunidad Adaptativa / Inmunoterapia / Melanoma / Modelos Biológicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Inmunidad Adaptativa / Inmunoterapia / Melanoma / Modelos Biológicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Nature Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos