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Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Roland, Bartholomew P; Amrich, Christopher G; Kammerer, Charles J; Stuchul, Kimberly A; Larsen, Samantha B; Rode, Sascha; Aslam, Anoshé A; Heroux, Annie; Wetzel, Ronald; VanDemark, Andrew P; Palladino, Michael J.
Afiliación
  • Roland BP; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Amrich CG; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
  • Kammerer CJ; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Stuchul KA; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Larsen SB; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Rode S; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Aslam AA; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
  • Heroux A; Department of Biology, Brookhaven National Laboratory, Upton, NY 11973, USA.
  • Wetzel R; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • VanDemark AP; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Palladino MJ; Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Pittsburgh Institute for Neurodegenerative Diseases (PIND), University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address: mjp44@pitt.edu.
Biochim Biophys Acta ; 1852(1): 61-9, 2015 Jan.
Article en En | MEDLINE | ID: mdl-25463631
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Triosa-Fosfato Isomerasa / Errores Innatos del Metabolismo de los Carbohidratos / Dominio Catalítico / Anemia Hemolítica Congénita no Esferocítica Límite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Triosa-Fosfato Isomerasa / Errores Innatos del Metabolismo de los Carbohidratos / Dominio Catalítico / Anemia Hemolítica Congénita no Esferocítica Límite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos