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Brincidofovir for polyomavirus-associated nephropathy after allogeneic hematopoietic stem cell transplantation.
Papanicolaou, Genovefa A; Lee, Yeon Joo; Young, James W; Seshan, Surya V; Boruchov, Adam M; Chittick, Gregory; Momméja-Marin, Herve; Glezerman, Ilya G.
Afiliación
  • Papanicolaou GA; Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY.
  • Lee YJ; Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
  • Young JW; Department of Medicine, Weill Cornell Medical College, New York, NY; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
  • Seshan SV; Department of Pathology, Weill Cornell Medical College, New York, NY.
  • Boruchov AM; Saint Francis Hospital and Medical Center and University of Connecticut School of Medicine, Hartford, CT.
  • Chittick G; Chimerix, Inc, Durham, NC.
  • Momméja-Marin H; Chimerix, Inc, Durham, NC.
  • Glezerman IG; Department of Medicine, Weill Cornell Medical College, New York, NY; Renal Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: glezermi@mskcc.org.
Am J Kidney Dis ; 65(5): 780-4, 2015 May.
Article en En | MEDLINE | ID: mdl-25600489
ABSTRACT
Polyomavirus-associated nephropathy (PVAN) is common in patients who have undergone kidney transplantation and has been reported in hematopoietic stem cell (HSC) transplant recipients. Aside from reduction of immunosuppression, few therapeutic options exist for treatment of PVAN. We report a case of PVAN in a severely immunocompromised allogeneic HSC transplant recipient that was treated with brincidofovir without reduction of immunosuppression. We review our institutional experience of PVAN in HSC transplantation and discuss the potential use of brincidofovir for treatment.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones Tumorales por Virus / Virus BK / Infecciones por Citomegalovirus / Trasplante de Células Madre Hematopoyéticas / Infecciones por Polyomavirus / Citosina / Organofosfonatos / Enfermedades Renales Tipo de estudio: Risk_factors_studies Límite: Humans / Male / Middle aged Idioma: En Revista: Am J Kidney Dis Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones Tumorales por Virus / Virus BK / Infecciones por Citomegalovirus / Trasplante de Células Madre Hematopoyéticas / Infecciones por Polyomavirus / Citosina / Organofosfonatos / Enfermedades Renales Tipo de estudio: Risk_factors_studies Límite: Humans / Male / Middle aged Idioma: En Revista: Am J Kidney Dis Año: 2015 Tipo del documento: Article