A case of advanced malignant pleural mesothelioma treatment with chemotherapy and photodynamic therapy.
Tuberc Respir Dis (Seoul)
; 78(1): 36-40, 2015 Jan.
Article
en En
| MEDLINE
| ID: mdl-25653696
ABSTRACT
Malignant pleural mesothelioma (MPM) is an aggressive, treatment-resistant, and generally fatal disease. A 68-year-old male who was diagnosed with MPM at another hospital came to our hospital with dyspnea. We advised him to take combination chemotherapy but he refused to take the treatment. That was because he had already received chemotherapy with supportive care at another hospital but his condition worsened. Thus, we recommended photodynamic therapy (PDT) to deal with the dyspnea and MPM. After PDT, the dyspnea improved and the patient then decided to take the combination chemotherapy. Our patient received chemotherapy using pemetrexed/cisplatin. Afterwards, he received a single PDT treatment and then later took chemotherapy using gemcitabine/cisplatin. The patient showed a survival time of 27 months, which is longer than median survival time in advanced MPM patients. Further research and clinical trials are needed to demonstrate any synergistic effect between the combination chemotherapy and PDT.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Tuberc Respir Dis (Seoul)
Año:
2015
Tipo del documento:
Article