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Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway.
Wang, May-Yun; Yan, Hai; Shi, Zhiqing; Evans, Matthew R; Yu, Xinxin; Lee, Young; Chen, Shiuhwei; Williams, Annie; Philippe, Jacques; Roth, Michael G; Unger, Roger H.
Afiliación
  • Wang MY; Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390;
  • Yan H; REMD Biotherapeutics, Inc., Camarillo, CA 93012; Beijing Cosci-REMD Biotherapeutics Inc., Beijing 102206, China;
  • Shi Z; REMD Biotherapeutics, Inc., Camarillo, CA 93012; Beijing Cosci-REMD Biotherapeutics Inc., Beijing 102206, China;
  • Evans MR; Department of Biochemistry and.
  • Yu X; Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390;
  • Lee Y; Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390;
  • Chen S; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390;
  • Williams A; University of Notre Dame, Notre Dame, IN 46556;
  • Philippe J; University of Geneva School of Medicine, 1211 Geneva, Switzerland; and.
  • Roth MG; Department of Biochemistry and roger.unger@utsouthwestern.edu michael.roth@utsouthwestern.edu.
  • Unger RH; Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390; Department of Medical Service, Veteran's Administration North Texas Health Care System, Dallas, TX 75216 roger.unger@utsouthwestern.edu michael.roth@utsouthwestern.edu.
Proc Natl Acad Sci U S A ; 112(8): 2503-8, 2015 Feb 24.
Article en En | MEDLINE | ID: mdl-25675519
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Glucagón / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 / Insulina / Anticuerpos Monoclonales Límite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Glucagón / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 / Insulina / Anticuerpos Monoclonales Límite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article