Amplification of IL-21 signalling pathway through Bruton's tyrosine kinase in human B cell activation.

Wang, Sheau-Pey; Iwata, Shigeru; Nakayamada, Shingo; Niiro, Hiroaki; Jabbarzadeh-Tabrizi, Siamak; Kondo, Masahiro; Kubo, Satoshi; Yoshikawa, Maiko; Tanaka, Yoshiya

Wang, Sheau-Pey; Iwata, Shigeru; Nakayamada, Shingo; Niiro, Hiroaki; Jabbarzadeh-Tabrizi, Siamak; Kondo, Masahiro; Kubo, Satoshi; Yoshikawa, Maiko; Tanaka, Yoshiya.

Afiliación

Wang SP; First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu and.
Iwata S; First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu and.
Nakayamada S; First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu and.
Niiro H; Graduate School of Medical Sciences, Department of Medicine and Biosystemic Science, Kyushu University, Fukuoka, Japan.
Jabbarzadeh-Tabrizi S; Graduate School of Medical Sciences, Department of Medicine and Biosystemic Science, Kyushu University, Fukuoka, Japan.
Kondo M; First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu and.
Kubo S; First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu and.
Yoshikawa M; First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu and.
Tanaka Y; First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu and tanaka@med.uoeh-u.ac.jp.

Rheumatology (Oxford) ; 54(8): 1488-97, 2015 Aug.

Article en En | MEDLINE | ID: mdl-25724205

Asunto(s)

Factor Activador de Células B/fisiología; Linfocitos B/fisiología; Antígenos CD40/fisiología; Interleucinas/fisiología; Proteínas Tirosina Quinasas/fisiología; Proteínas Proto-Oncogénicas c-bcr/fisiología; Transducción de Señal/fisiología; Agammaglobulinemia Tirosina Quinasa; Anciano; Artritis Reumatoide/metabolismo; Artritis Reumatoide/patología; Artritis Reumatoide/fisiopatología; Linfocitos B/efectos de los fármacos; Linfocitos B/patología; Antígenos CD40/farmacología; Estudios de Casos y Controles; Diferenciación Celular/efectos de los fármacos; Línea Celular; Células Cultivadas; Femenino; Técnicas de Silenciamiento del Gen; Humanos; Técnicas In Vitro; Interleucinas/farmacología; Masculino; Persona de Mediana Edad; Fosforilación; Proteínas Tirosina Quinasas/genética; Proteínas Proto-Oncogénicas c-bcr/farmacología; Factor Reumatoide/metabolismo; Factor de Transcripción STAT1/metabolismo

Palabras clave

B cells; BCR signalling; IL-21; STAT1; autoimmune diseases; class-switch DNA recombination; rheumatoid arthritis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Tirosina Quinasas / Linfocitos B / Transducción de Señal / Interleucinas / Antígenos CD40 / Proteínas Proto-Oncogénicas c-bcr / Factor Activador de Células B Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Rheumatology (Oxford) Asunto de la revista: REUMATOLOGIA Año: 2015 Tipo del documento: Article

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