FOXO1 deletion reduces dendritic cell function and enhances susceptibility to periodontitis.

Xiao, Wenmei; Dong, Guangyu; Pacios, Sandra; Alnammary, Maher; Barger, Laura A; Wang, Yu; Wu, Yingying; Graves, Dana T

Xiao, Wenmei; Dong, Guangyu; Pacios, Sandra; Alnammary, Maher; Barger, Laura A; Wang, Yu; Wu, Yingying; Graves, Dana T.

Afiliación

Xiao W; Department of Periodontology, School and Hospital of Stomatology, Peking University, Beijing, China; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Dong G; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Pacios S; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Alnammary M; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Barger LA; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Wang Y; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Implantology, School of Stomatology, Jilin University, Changchun, China.
Wu Y; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Graves DT; Department of Periodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: dtgraves@dental.upenn.edu.

Am J Pathol ; 185(4): 1085-93, 2015 Apr.

Article en En | MEDLINE | ID: mdl-25794707

Asunto(s)

Células Dendríticas/metabolismo; Factores de Transcripción Forkhead/metabolismo; Eliminación de Gen; Periodontitis/metabolismo; Periodontitis/patología; Inmunidad Adaptativa; Pérdida de Hueso Alveolar/complicaciones; Pérdida de Hueso Alveolar/patología; Animales; Antígeno CD11c/metabolismo; Recuento de Células; Linaje de la Célula; Citocinas/metabolismo; Susceptibilidad a Enfermedades; Proteína Forkhead Box O1; Encía/metabolismo; Encía/microbiología; Encía/patología; Mediadores de Inflamación/metabolismo; Ganglios Linfáticos/metabolismo; Ratones; Osteoclastos/metabolismo; Osteoclastos/patología; Periodontitis/inmunología; Periodontitis/microbiología; Porphyromonas gingivalis/fisiología; ARN Mensajero/genética; ARN Mensajero/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Periodontitis / Células Dendríticas / Eliminación de Gen / Factores de Transcripción Forkhead Límite: Animals Idioma: En Revista: Am J Pathol Año: 2015 Tipo del documento: Article

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