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Trastuzumab triggers phagocytic killing of high HER2 cancer cells in vitro and in vivo by interaction with Fcγ receptors on macrophages.
Shi, Yun; Fan, Xuejun; Deng, Hui; Brezski, Randall J; Rycyzyn, Michael; Jordan, Robert E; Strohl, William R; Zou, Quanming; Zhang, Ningyan; An, Zhiqiang.
Afiliación
  • Shi Y; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Mil
  • Fan X; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030;
  • Deng H; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030;
  • Brezski RJ; Biologics Research, Janssen Research & Development, LLC, Spring House, PA 19002.
  • Rycyzyn M; Biologics Research, Janssen Research & Development, LLC, Spring House, PA 19002.
  • Jordan RE; Biologics Research, Janssen Research & Development, LLC, Spring House, PA 19002.
  • Strohl WR; Biologics Research, Janssen Research & Development, LLC, Spring House, PA 19002.
  • Zou Q; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Chongqing 400038, People's Republic of China; and.
  • Zhang N; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030; zhiqiang.an@uth.tmc.edu Ningyan.zhang@uth.tmc.edu.
  • An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030; zhiqiang.an@uth.tmc.edu Ningyan.zhang@uth.tmc.edu.
J Immunol ; 194(9): 4379-86, 2015 May 01.
Article en En | MEDLINE | ID: mdl-25795760
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fagocitosis / Receptores de IgG / Receptor ErbB-2 / Anticuerpos Monoclonales Humanizados / Macrófagos / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: J Immunol Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fagocitosis / Receptores de IgG / Receptor ErbB-2 / Anticuerpos Monoclonales Humanizados / Macrófagos / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: J Immunol Año: 2015 Tipo del documento: Article