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A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.
Carmona, F David; Mackie, Sarah L; Martín, Jose-Ezequiel; Taylor, John C; Vaglio, Augusto; Eyre, Stephen; Bossini-Castillo, Lara; Castañeda, Santos; Cid, Maria C; Hernández-Rodríguez, José; Prieto-González, Sergio; Solans, Roser; Ramentol-Sintas, Marc; González-Escribano, M Francisca; Ortiz-Fernández, Lourdes; Morado, Inmaculada C; Narváez, Javier; Miranda-Filloy, José A; Beretta, Lorenzo; Lunardi, Claudio; Cimmino, Marco A; Gianfreda, Davide; Santilli, Daniele; Ramirez, Giuseppe A; Soriano, Alessandra; Muratore, Francesco; Pazzola, Giulia; Addimanda, Olga; Wijmenga, Cisca; Witte, Torsten; Schirmer, Jan H; Moosig, Frank; Schönau, Verena; Franke, Andre; Palm, Øyvind; Molberg, Øyvind; Diamantopoulos, Andreas P; Carette, Simon; Cuthbertson, David; Forbess, Lindsy J; Hoffman, Gary S; Khalidi, Nader A; Koening, Curry L; Langford, Carol A; McAlear, Carol A; Moreland, Larry; Monach, Paul A; Pagnoux, Christian; Seo, Philip; Spiera, Robert.
Afiliación
  • Carmona FD; Instituto de Parasitología y Biomedicina "López-Neyra," CSIC, PTS Granada, Granada 18016, Spain. Electronic address: dcarmona@ipb.csic.es.
  • Mackie SL; Leeds Institute of Rheumatic and Musculoskeletal Medicine and NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds LS7 4SA, UK.
  • Martín JE; Instituto de Parasitología y Biomedicina "López-Neyra," CSIC, PTS Granada, Granada 18016, Spain.
  • Taylor JC; School of Medicine and NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds LS9 7TF, UK.
  • Vaglio A; Unit of Nephrology, University Hospital of Parma, Parma 43126, Italy.
  • Eyre S; NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, Manchester, UK; Arthritis Research UK Epidemiology Unit, University Of Manchester, Manchester M13 9NT, UK.
  • Bossini-Castillo L; Instituto de Parasitología y Biomedicina "López-Neyra," CSIC, PTS Granada, Granada 18016, Spain.
  • Castañeda S; Department of Rheumatology, Hospital de la Princesa, IIS-Princesa, Madrid 28006, Spain.
  • Cid MC; Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona 08036, Spain.
  • Hernández-Rodríguez J; Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona 08036, Spain.
  • Prieto-González S; Vasculitis Research Unit, Department of Autoimmune Diseases, Hospital Clínic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona 08036, Spain.
  • Solans R; Autoimmune Systemic Diseases Unit, Department of Internal Medicine, Hospital Vall d'Hebron, Autonomous University of Barcelona, Barcelona 08035, Spain.
  • Ramentol-Sintas M; Autoimmune Systemic Diseases Unit, Department of Internal Medicine, Hospital Vall d'Hebron, Autonomous University of Barcelona, Barcelona 08035, Spain.
  • González-Escribano MF; Department of Immunology, Hospital Universitario Virgen del Rocío (IBiS, CSIC, US), Sevilla 41013, Spain.
  • Ortiz-Fernández L; Department of Immunology, Hospital Universitario Virgen del Rocío (IBiS, CSIC, US), Sevilla 41013, Spain.
  • Morado IC; Department of Rheumatology, Hospital Clínico San Carlos, Madrid 28040, Spain.
  • Narváez J; Department of Rheumatology, Hospital Universitario de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, Barcelona 08907, Spain.
  • Miranda-Filloy JA; Department of Rheumatology, Hospital Xeral-Calde, Lugo 27004, Spain.
  • Beretta L; Referral Center for Systemic Autoimmune Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Milan 20122, Italy.
  • Lunardi C; Department of Medicine, Universita degli Studi di Verona, Verona 37134, Italy.
  • Cimmino MA; Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genova 16132, Italy.
  • Gianfreda D; Department of Clinical and Experimental Medicine, University of Parma, School of Medicine, Parma 43126, Italy.
  • Santilli D; Unit of Internal Medicine and Rheumatology, University Hospital of Parma, Parma 43126, Italy.
  • Ramirez GA; Unit of Internal Medicine and Immunology, IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milan 20132, Italy.
  • Soriano A; Department of Clinical Medicine and Rheumatology, Campus Bio-Medico University, Rome 00128, Italy.
  • Muratore F; Rheumatology Unit, Department of Internal Medicine, Azienda Ospedaliera Arcispedale Santa Maria Nuova, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia 42123, Italy.
  • Pazzola G; Rheumatology Unit, Department of Internal Medicine, Azienda Ospedaliera Arcispedale Santa Maria Nuova, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia 42123, Italy.
  • Addimanda O; Rheumatology Unit, Department of Internal Medicine, Azienda Ospedaliera Arcispedale Santa Maria Nuova, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia 42123, Italy.
  • Wijmenga C; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9700, the Netherlands.
  • Witte T; Hannover Medical School, Hannover 30625, Germany.
  • Schirmer JH; Vasculitis Clinic, Klinikum Bad Bramstedt & University Hospital of Schleswig Holstein, Bad Bramstedt 24576, Germany.
  • Moosig F; Vasculitis Clinic, Klinikum Bad Bramstedt & University Hospital of Schleswig Holstein, Bad Bramstedt 24576, Germany.
  • Schönau V; Department of Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen 91054, Germany.
  • Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel 24105, Germany.
  • Palm Ø; Department of Rheumatology, Oslo University Hospital, Oslo 0424, Norway.
  • Molberg Ø; Department of Rheumatology, Oslo University Hospital, Oslo 0424, Norway.
  • Diamantopoulos AP; Department of Rheumatology, Hospital of Southern Norway Trust, Kristiansand 4604, Norway.
  • Carette S; Division of Rheumatology, Mount Sinai Hospital, Toronto, ON M5T 3L9, Canada.
  • Cuthbertson D; Department of Biostatistics, University of South Florida, Tampa, FL 33612, USA.
  • Forbess LJ; Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Hoffman GS; Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
  • Khalidi NA; Division of Rheumatology, St. Joseph's Healthcare, McMaster University, Hamilton, ON L8N 1Y2, Canada.
  • Koening CL; Division of Rheumatology, University of Utah, Salt Lake City, UT 84132, USA.
  • Langford CA; Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
  • McAlear CA; Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Moreland L; Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Monach PA; Section of Rheumatology, Boston University School of Medicine, Boston, MA 02118, USA.
  • Pagnoux C; Division of Rheumatology, Mount Sinai Hospital, Toronto, ON M5T 3L9, Canada.
  • Seo P; Division of Rheumatology, Johns Hopkins University, Baltimore, MD 21224, USA.
  • Spiera R; Department of Rheumatology, Hospital for Special Surgery, New York, NY 10021, USA.
Am J Hum Genet ; 96(4): 565-80, 2015 Apr 02.
Article en En | MEDLINE | ID: mdl-25817017
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Arteritis de Células Gigantes / Genes MHC Clase II / Herencia Multifactorial Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Arteritis de Células Gigantes / Genes MHC Clase II / Herencia Multifactorial Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2015 Tipo del documento: Article