[To the question of the optimization of methods for detection of vinyl chloride and 1,2-dichloroethane, and their metabolites in biological fluids in workers involved in production of polyvinyl chloride].
Gig Sanit
; (5): 116-20, 2014.
Article
en Ru
| MEDLINE
| ID: mdl-25831943
ABSTRACT
There is considered the improvement of methodological approaches to the gas chromatographic methods- of the detection of vinyl chloride and 1,2-dichloroethane and their metabolites--chloroethanol and monochloroacetic acid in biological fluids. There were evaluated such metrological characteristics of methods, as repeatability, interlaboratoty precision, relevance and accuracy. The value of relative expanded uncertainty does not exceed 30%. There are reported optimal regimes of gas chromatographic analysis, conditions for sample preparation. The results of the contents ofthese chemical compounds and their metabolites in biological fluids from persons working in contact with chlorinated hydrocarbons are presented These techniques can be used for the detection ofthe fact of exposure to toxic substances, assessment of the level of exposure and biomonitoring.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Cloruro de Polivinilo
/
Cloruro de Vinilo
/
Industria Química
/
Cromatografía de Gases
/
Exposición Profesional
/
Contaminantes Ocupacionales del Aire
/
Dicloruros de Etileno
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
Ru
Revista:
Gig Sanit
Año:
2014
Tipo del documento:
Article