AVIA v2.0: annotation, visualization and impact analysis of genomic variants and genes.

ABSTRACT

UNLABELLED As sequencing becomes cheaper and more widely available, there is a greater need to quickly and effectively analyze large-scale genomic data. While the functionality of AVIA v1.0, whose implementation was based on ANNOVAR, was comparable with other annotation web servers, AVIA v2.0 represents an enhanced web-based server that extends genomic annotations to cell-specific transcripts and protein-level functional annotations. With AVIA's improved interface, users can better visualize their data, perform comprehensive searches and categorize both coding and non-coding variants. AVAILABILITY AND IMPLEMENTATION AVIA is freely available through the web at http//avia.abcc.ncifcrf.gov. CONTACT Hue.Vuong@fnlcr.nih.gov SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.