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Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model.
Gerenu, Gorka; Liu, Kai; Chojnacki, Jeremy E; Saathoff, John M; Martínez-Martín, Pablo; Perry, George; Zhu, Xiongwei; Lee, Hyoung-Gon; Zhang, Shijun.
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  • Gerenu G; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Liu K; Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia, USA.
  • Chojnacki JE; Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia, USA.
  • Saathoff JM; Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia, USA.
  • Martínez-Martín P; Alzheimer Disease Research Unit, Alzheimer Center Reina Sofía Foundation, CIEN Foundation, Carlos III Institute of Health, Madrid, Spain.
  • Perry G; College of Sciences, University of Texas, San Antonio, Texas, USA.
  • Zhu X; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Lee HG; Neurology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Zhang S; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
ACS Chem Neurosci ; 6(8): 1393-1399, 2015 Aug 19.
Article en En | MEDLINE | ID: mdl-25893520
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Pentanoicos / Fármacos Neuroprotectores / Cumarinas / Enfermedad de Alzheimer / Indoles / Melatonina Límite: Animals Idioma: En Revista: ACS Chem Neurosci Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Pentanoicos / Fármacos Neuroprotectores / Cumarinas / Enfermedad de Alzheimer / Indoles / Melatonina Límite: Animals Idioma: En Revista: ACS Chem Neurosci Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos