One-Pot Synthesis of Brightly Fluorescent Mes2B-Functionalized Indolizine Derivatives via Cycloaddition Reactions.
Org Lett
; 17(10): 2486-9, 2015 May 15.
Article
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| MEDLINE
| ID: mdl-25915087
ABSTRACT
Four new BMes2-functionalized indolizine derivatives (Mes = mesityl) have been prepared via the cycloaddition reaction between pyrido[2,1-a]isoindole (A) or pyrrolo[1,2-a]pyridine (B) and BMes2-containing alkynes. All four compounds are brightly blue or blue-green fluorescent with λ(em) = 428-495 nm and Φ = 0.27-0.68, depending on the substitution position of the BMes2 group. Experimental and TD-DFT computational data indicated that the primary electronic transitions responsible for the fluorescence of 1-4 are from HOMO to LUMO (π â π*) rather than charge transfer from N â B, which is in agreement with previous findings suggesting that the lone-pair on N is delocalized throughout the N-heterocycles.
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Canadá