Cyclic di-GMP modulates gene expression in Lyme disease spirochetes at the tick-mammal interface to promote spirochete survival during the blood meal and tick-to-mammal transmission.

Caimano, Melissa J; Dunham-Ems, Star; Allard, Anna M; Cassera, Maria B; Kenedy, Melisha; Radolf, Justin D

Caimano, Melissa J; Dunham-Ems, Star; Allard, Anna M; Cassera, Maria B; Kenedy, Melisha; Radolf, Justin D.

Afiliación

Caimano MJ; Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA Department of Pediatrics, University of Connecticut Health Center, Farmington, Connecticut, USA Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, Connectic
Dunham-Ems S; Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA.
Allard AM; Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA.
Cassera MB; Department of Biochemistry and Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia, USA.
Kenedy M; Department of Microbiology and Immunology, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma, USA.
Radolf JD; Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, USA Department of Pediatrics, University of Connecticut Health Center, Farmington, Connecticut, USA Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, Connectic

Infect Immun ; 83(8): 3043-60, 2015 Aug.

Article en En | MEDLINE | ID: mdl-25987708

Asunto(s)

Proteínas Bacterianas/genética; Borrelia burgdorferi/crecimiento & desarrollo; Borrelia burgdorferi/metabolismo; GMP Cíclico/análogos & derivados; Regulación Bacteriana de la Expresión Génica; Enfermedad de Lyme/microbiología; Garrapatas/microbiología; Animales; Proteínas Bacterianas/metabolismo; Borrelia burgdorferi/genética; GMP Cíclico/metabolismo; Femenino; Humanos; Enfermedad de Lyme/transmisión; Ratones; Ratones Endogámicos C3H; Viabilidad Microbiana; Ratas; Ratas Sprague-Dawley; Garrapatas/fisiología

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Garrapatas / Proteínas Bacterianas / Enfermedad de Lyme / Regulación Bacteriana de la Expresión Génica / GMP Cíclico / Borrelia burgdorferi Límite: Animals / Female / Humans Idioma: En Revista: Infect Immun Año: 2015 Tipo del documento: Article

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