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The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice.
Cui, Shuaiying; Lim, Kim-Chew; Shi, Lihong; Lee, Mary; Jearawiriyapaisarn, Natee; Myers, Greggory; Campbell, Andrew; Harro, David; Iwase, Shigeki; Trievel, Raymond C; Rivers, Angela; DeSimone, Joseph; Lavelle, Donald; Saunthararajah, Yogen; Engel, James Douglas.
Afiliación
  • Cui S; Department of Cell and Developmental Biology.
  • Lim KC; Department of Cell and Developmental Biology.
  • Shi L; Department of Cell and Developmental Biology.
  • Lee M; Department of Cell and Developmental Biology.
  • Jearawiriyapaisarn N; Department of Cell and Developmental Biology.
  • Myers G; Department of Cell and Developmental Biology.
  • Campbell A; Department of Pediatrics and Infectious Diseases.
  • Harro D; Department of Pathology.
  • Iwase S; Department of Human Genetics, and.
  • Trievel RC; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI;
  • Rivers A; Jesse Brown VA Medical Center, Department of Pediatrics, and.
  • DeSimone J; Department of Pediatrics, and Department of Medicine, University of Illinois at Chicago, Chicago, IL; and.
  • Lavelle D; Department of Pediatrics, and Department of Medicine, University of Illinois at Chicago, Chicago, IL; and.
  • Saunthararajah Y; Cleveland Clinic, Cleveland, OH.
  • Engel JD; Department of Cell and Developmental Biology.
Blood ; 126(3): 386-96, 2015 Jul 16.
Article en En | MEDLINE | ID: mdl-26031919

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Rodaminas / Compuestos de Espiro / Esplenomegalia / Tiofenos / Hemoglobina Fetal / Histona Demetilasas / Anemia de Células Falciformes Límite: Animals / Humans Idioma: En Revista: Blood Año: 2015 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Rodaminas / Compuestos de Espiro / Esplenomegalia / Tiofenos / Hemoglobina Fetal / Histona Demetilasas / Anemia de Células Falciformes Límite: Animals / Humans Idioma: En Revista: Blood Año: 2015 Tipo del documento: Article