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JAK inhibition induces silencing of T Helper cytokine secretion and a profound reduction in T regulatory cells.
Keohane, Clodagh; Kordasti, Shahram; Seidl, Thomas; Perez Abellan, Pilar; Thomas, Nicholas S B; Harrison, Claire N; McLornan, Donal P; Mufti, Ghulam J.
Afiliación
  • Keohane C; Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
  • Kordasti S; Department of Haematological Medicine, Kings College London, London, UK.
  • Seidl T; Department of Haematological Medicine, Kings College London, London, UK.
  • Perez Abellan P; Department of Haematological Medicine, Kings College Hospital NHS Foundation Trust, London, UK.
  • Thomas NS; Department of Haematological Medicine, Kings College London, London, UK.
  • Harrison CN; Department of Haematological Medicine, Kings College London, London, UK.
  • McLornan DP; Department of Haematological Medicine, Kings College London, London, UK.
  • Mufti GJ; Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Br J Haematol ; 171(1): 60-73, 2015 Oct.
Article en En | MEDLINE | ID: mdl-26075866
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirazoles / Pirrolidinas / Sulfonamidas / Linfocitos T Reguladores / Inhibidores de Proteínas Quinasas / Quinasas Janus / Trastornos Mieloproliferativos Límite: Female / Humans / Male Idioma: En Revista: Br J Haematol Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirazoles / Pirrolidinas / Sulfonamidas / Linfocitos T Reguladores / Inhibidores de Proteínas Quinasas / Quinasas Janus / Trastornos Mieloproliferativos Límite: Female / Humans / Male Idioma: En Revista: Br J Haematol Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido