Ca(2+) clearance by plasmalemmal NCLX, Li(+)-permeable Na(+)/Ca(2+) exchanger, is required for the sustained exocytosis in rat insulinoma INS-1 cells.

Han, Young-Eun; Ryu, Shin-Young; Park, Sun-Hyun; Lee, Kyu-Hee; Lee, Suk-Ho; Ho, Won-Kyung

Han, Young-Eun; Ryu, Shin-Young; Park, Sun-Hyun; Lee, Kyu-Hee; Lee, Suk-Ho; Ho, Won-Kyung.

Afiliación

Han YE; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Ryu SY; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Park SH; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Lee KH; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Lee SH; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea.
Ho WK; Department of Physiology and Biomembrane Plasticity Research Center, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, Republic of Korea. wonkyung@snu.ac.kr.

Pflugers Arch ; 467(12): 2461-72, 2015 Dec.

Article en En | MEDLINE | ID: mdl-26100674

Asunto(s)

Calcio/metabolismo; Membrana Celular/metabolismo; Exocitosis; Células Secretoras de Insulina/metabolismo; Litio/metabolismo; Intercambiador de Sodio-Calcio/metabolismo; Potenciales de Acción; Animales; Línea Celular Tumoral; Células Cultivadas; Células Secretoras de Insulina/efectos de los fármacos; Potencial de la Membrana Mitocondrial; Ratones; Ratones Endogámicos C57BL; Péptidos/farmacología; Ratas; Intercambiador de Sodio-Calcio/genética

Palabras clave

Ca2+ transport; Capacitance; Exocytosis; Na+/Ca2+ exchanger; Pancreatic ß-cell

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Membrana Celular / Calcio / Intercambiador de Sodio-Calcio / Células Secretoras de Insulina / Exocitosis / Litio Límite: Animals Idioma: En Revista: Pflugers Arch Año: 2015 Tipo del documento: Article

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