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Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages.
Christofidou, Paraskevi; Nelson, Christopher P; Nikpay, Majid; Qu, Liming; Li, Mingyao; Loley, Christina; Debiec, Radoslaw; Braund, Peter S; Denniff, Matthew; Charchar, Fadi J; Arjo, Ares Rocanin; Trégouët, David-Alexandre; Goodall, Alison H; Cambien, Francois; Ouwehand, Willem H; Roberts, Robert; Schunkert, Heribert; Hengstenberg, Christian; Reilly, Muredach P; Erdmann, Jeanette; McPherson, Ruth; König, Inke R; Thompson, John R; Samani, Nilesh J; Tomaszewski, Maciej.
Afiliación
  • Christofidou P; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK.
  • Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK; NIHR Biomedical Research Unit in Cardiovascular Disease, Leicester LE3 9QP, UK.
  • Nikpay M; Ruddy Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, ON K1Y 4W7, Canada; Atherogenomics Laboratory, University of Ottawa Heart Institute, Ottawa, ON K1Y 3V5, Canada.
  • Qu L; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Li M; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Loley C; Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck 23562, Germany.
  • Debiec R; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK.
  • Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK.
  • Denniff M; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK.
  • Charchar FJ; Faculty of Science and Technology, School of Applied and Biomedical Sciences, Federation University Australia, Ballarat, VIC 3350, Australia.
  • Arjo AR; ICAN Institute for Cardiometabolism and Nutrition, Paris 75013, France; INSERM, UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris 75013, France; Sorbonne Universités, UPMC University, Paris 06, UMR_S 1166, Paris 75013, France.
  • Trégouët DA; ICAN Institute for Cardiometabolism and Nutrition, Paris 75013, France; INSERM, UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris 75013, France; Sorbonne Universités, UPMC University, Paris 06, UMR_S 1166, Paris 75013, France.
  • Goodall AH; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK; NIHR Biomedical Research Unit in Cardiovascular Disease, Leicester LE3 9QP, UK.
  • Cambien F; ICAN Institute for Cardiometabolism and Nutrition, Paris 75013, France; INSERM, UMR_S 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris 75013, France; Sorbonne Universités, UPMC University, Paris 06, UMR_S 1166, Paris 75013, France.
  • Ouwehand WH; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge and NHS Blood and Transplant, Cambridge CB2 0PT, UK; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.
  • Roberts R; Ruddy Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, ON K1Y 4W7, Canada; Atherogenomics Laboratory, University of Ottawa Heart Institute, Ottawa, ON K1Y 3V5, Canada.
  • Schunkert H; Deutsches Herzzentrum München, Technische Universität München, Munich 80636, Germany; Deutsches Zentrum für Herz- und Kreislauf-Forschung (DZHK), Munich 80636, Germany.
  • Hengstenberg C; Deutsches Herzzentrum München, Technische Universität München, Munich 80636, Germany; Deutsches Zentrum für Herz- und Kreislauf-Forschung (DZHK), Munich 80636, Germany.
  • Reilly MP; Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19148, USA.
  • Erdmann J; Institute for Integrative and Experimental Genomics, University of Lübeck, Lübeck 23562, Germany.
  • McPherson R; Ruddy Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, ON K1Y 4W7, Canada; Atherogenomics Laboratory, University of Ottawa Heart Institute, Ottawa, ON K1Y 3V5, Canada.
  • König IR; Institute of Medical Biometry and Statistics, University of Lübeck, Lübeck 23562, Germany.
  • Thompson JR; Department of Health Sciences, University of Leicester, Leicester LE1 7RH, UK.
  • Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK; NIHR Biomedical Research Unit in Cardiovascular Disease, Leicester LE3 9QP, UK.
  • Tomaszewski M; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK; NIHR Biomedical Research Unit in Cardiovascular Disease, Leicester LE3 9QP, UK. Electronic address: mt142@le.ac.uk.
Am J Hum Genet ; 97(2): 228-37, 2015 Aug 06.
Article en En | MEDLINE | ID: mdl-26166477
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Monocitos / Regulación de la Expresión Génica / Genes Recesivos / Homocigoto / Macrófagos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Monocitos / Regulación de la Expresión Génica / Genes Recesivos / Homocigoto / Macrófagos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2015 Tipo del documento: Article País de afiliación: Reino Unido