Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia.

Park, I-K; Mundy-Bosse, B; Whitman, S P; Zhang, X; Warner, S L; Bearss, D J; Blum, W; Marcucci, G; Caligiuri, M A

Park, I-K; Mundy-Bosse, B; Whitman, S P; Zhang, X; Warner, S L; Bearss, D J; Blum, W; Marcucci, G; Caligiuri, M A.

Afiliación

Park IK; Comprehensive Cancer Center and The James Cancer Hospital, The Ohio State University, Columbus, OH, USA.
Mundy-Bosse B; Comprehensive Cancer Center and The James Cancer Hospital, The Ohio State University, Columbus, OH, USA.
Whitman SP; Comprehensive Cancer Center and The James Cancer Hospital, The Ohio State University, Columbus, OH, USA.
Zhang X; Center for Biostatistics, The Ohio State University, Columbus, OH, USA.
Warner SL; Tolero Pharmaceuticals, Inc., Lehi, UT, USA.
Bearss DJ; Tolero Pharmaceuticals, Inc., Lehi, UT, USA.
Blum W; Comprehensive Cancer Center and The James Cancer Hospital, The Ohio State University, Columbus, OH, USA.
Marcucci G; Division of Hematology, Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH, USA.
Caligiuri MA; Comprehensive Cancer Center and The James Cancer Hospital, The Ohio State University, Columbus, OH, USA.

Leukemia ; 29(12): 2382-9, 2015 Dec.

Article en En | MEDLINE | ID: mdl-26172401

Asunto(s)

Leucemia Mieloide Aguda/tratamiento farmacológico; Inhibidores de Proteínas Quinasas/uso terapéutico; Proteínas Proto-Oncogénicas/fisiología; Proteínas Tirosina Quinasas Receptoras/fisiología; Tirosina Quinasa 3 Similar a fms/antagonistas & inhibidores; Línea Celular Tumoral; Resistencia a Antineoplásicos; Humanos; Fosforilación; Tirosina Quinasa del Receptor Axl

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Proteínas Proto-Oncogénicas / Proteínas Tirosina Quinasas Receptoras / Inhibidores de Proteínas Quinasas / Tirosina Quinasa 3 Similar a fms Límite: Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

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