Optical Control of Microtubule Dynamics in Time and Space.
Cell
; 162(2): 243-245, 2015 Jul 16.
Article
en En
| MEDLINE
| ID: mdl-26186185
ABSTRACT
Small molecule inhibitors of microtubule dynamics are widely used as cell biology research tools and clinically as cancer chemotherapeutics. By slight modification to the chemical structure of a known microtubule inhibitor, combretastatin A-4, Borowiak et al. develop a photoswitchable derivative that can be turned "on" and "off" with low-intensity light to spatially and temporally control microtubule dynamics.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Estilbenos
/
Muerte Celular
/
Antimitóticos
/
Microtúbulos
/
Mitosis
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Cell
Año:
2015
Tipo del documento:
Article
País de afiliación:
Estados Unidos