Diastereo- and Enantioselective Iridium Catalyzed Carbonyl (α-Cyclopropyl)allylation via Transfer Hydrogenation.
Chemistry
; 21(37): 12903-7, 2015 Sep 07.
Article
en En
| MEDLINE
| ID: mdl-26235369
ABSTRACT
The first examples of diastereo- and enantioselective carbonyl α-(cyclopropyl)allylation are reported. Under the conditions of iridium catalyzed transfer hydrogenation using the chiral precatalyst (R)-Ir-I modified by SEGPHOS, carbonyl α-(cyclopropyl)allylation may be achieved with equal facility from alcohol or aldehyde oxidation levels. This methodology provides a conduit to hitherto inaccessible inaccessible enantiomerically enriched cyclopropane-containing architectures.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ciclopropanos
/
Hidrogenación
/
Iridio
Idioma:
En
Revista:
Chemistry
Asunto de la revista:
QUIMICA
Año:
2015
Tipo del documento:
Article