Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming growth factor ß-dependent manner in human osteosarcoma.

Jiang, Xuan; Shan, Jinlu; Dai, Nan; Zhong, Zhaoyang; Qing, Yi; Yang, Yuxing; Zhang, Shiheng; Li, Chongyi; Sui, Jiangdong; Ren, Tao; Li, Mengxia; Wang, Dong

Jiang, Xuan; Shan, Jinlu; Dai, Nan; Zhong, Zhaoyang; Qing, Yi; Yang, Yuxing; Zhang, Shiheng; Li, Chongyi; Sui, Jiangdong; Ren, Tao; Li, Mengxia; Wang, Dong.

Afiliación

Jiang X; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Shan J; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Dai N; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Zhong Z; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Qing Y; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Yang Y; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Zhang S; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Li C; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Sui J; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Ren T; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Li M; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
Wang D; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.

Cancer Sci ; 106(10): 1394-401, 2015 Oct.

Article en En | MEDLINE | ID: mdl-26250694

Asunto(s)

Neoplasias Óseas/irrigación sanguínea; ADN-(Sitio Apurínico o Apirimidínico) Liasa/metabolismo; Neovascularización Patológica/patología; Osteosarcoma/irrigación sanguínea; Factor de Crecimiento Transformador beta/metabolismo; Animales; Neoplasias Óseas/patología; Línea Celular Tumoral; Movimiento Celular; ADN-(Sitio Apurínico o Apirimidínico) Liasa/genética; Femenino; Células Endoteliales de la Vena Umbilical Humana/patología; Humanos; Masculino; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Invasividad Neoplásica/patología; Neovascularización Patológica/enzimología; Osteosarcoma/patología; Fosforilación; Pronóstico; Interferencia de ARN; ARN Interferente Pequeño; Transducción de Señal; Proteína smad3/metabolismo; Factor de Crecimiento Transformador beta/biosíntesis; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

Angiogenesis; apurinic/apyrimidinic endonuclease 1 (APE1); osteosarcoma; redox; transforming growth factor ß (TGFß)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Óseas / Osteosarcoma / Factor de Crecimiento Transformador beta / ADN-(Sitio Apurínico o Apirimidínico) Liasa / Neovascularización Patológica Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Sci Año: 2015 Tipo del documento: Article País de afiliación: China

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