Tumor Necrosis Factor-&#945; (TNF&#945;)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death.

Hernández-Corbacho, María José; Canals, Daniel; Adada, Mohamad M; Liu, Mengling; Senkal, Can E; Yi, Jae Kyo; Mao, Cungui; Luberto, Chiara; Hannun, Yusuf A; Obeid, Lina M

Tumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death.

Hernández-Corbacho, María José; Canals, Daniel; Adada, Mohamad M; Liu, Mengling; Senkal, Can E; Yi, Jae Kyo; Mao, Cungui; Luberto, Chiara; Hannun, Yusuf A; Obeid, Lina M.

Afiliación

Hernández-Corbacho MJ; From the Stony Brook Cancer Center, the Department of Medicine, and.
Canals D; From the Stony Brook Cancer Center, the Department of Medicine, and.
Adada MM; From the Stony Brook Cancer Center, the Department of Medicine, and.
Liu M; From the Stony Brook Cancer Center, the Department of Medicine, and.
Senkal CE; From the Stony Brook Cancer Center, the Department of Medicine, and.
Yi JK; From the Stony Brook Cancer Center, the Department of Medicine, and.
Mao C; From the Stony Brook Cancer Center, the Department of Medicine, and.
Luberto C; From the Stony Brook Cancer Center, the Department of Physiology and Biophysics, Stony Brook University, Health Sciences Center, Stony Brook, New York 11794 and.
Hannun YA; From the Stony Brook Cancer Center, the Department of Medicine, and.
Obeid LM; From the Stony Brook Cancer Center, the Department of Medicine, and the Northport Veterans Affairs Medical Center, Northport, New York 11768 lina.obeid@stonybrookmedicine.edu.

J Biol Chem ; 290(42): 25356-73, 2015 Oct 16.

Article en En | MEDLINE | ID: mdl-26318452

Asunto(s)

Apoptosis; Ceramidas/biosíntesis; Proteína-Tirosina Quinasas de Adhesión Focal/metabolismo; Oxidorreductasas/metabolismo; Factor de Necrosis Tumoral alfa/fisiología; Caspasas/metabolismo; Activación Enzimática; Proteína-Tirosina Quinasas de Adhesión Focal/antagonistas & inhibidores; Fumonisinas/farmacología; Técnicas de Silenciamiento del Gen; Humanos; Células MCF-7; Oxidorreductasas/genética; Factor de Necrosis Tumoral alfa/antagonistas & inhibidores

Palabras clave

Ceramide; PTK2 protein tyrosine kinase 2 (PTK2) (focal adhesion kinase) (FAK); cell death; ceramide synthase; fumonisin b1; plasma membrane; sphingolipid

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxidorreductasas / Ceramidas / Factor de Necrosis Tumoral alfa / Apoptosis / Proteína-Tirosina Quinasas de Adhesión Focal Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2015 Tipo del documento: Article

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