Folate receptor autoantibodies in pregnancy related complications.
Birth Defects Res A Clin Mol Teratol
; 103(12): 1028-30, 2015 Dec.
Article
en En
| MEDLINE
| ID: mdl-26390016
ABSTRACT
BACKGROUND:
Folate receptor autoantibodies in women have been associated with neural tube pregnancy and in children with cerebral folate deficiency syndrome and autism. These autoantibodies have been implicated in blocking folate transport to the fetus and to the brain in infants.METHODS:
We report a woman with multiple pregnancy related complications who was diagnosed with autoantibodies to the folate receptor alpha.RESULTS:
A treatment strategy with folate supplementation and reducing the antibody titer proved effective in normal pregnancy outcome.CONCLUSION:
This long-term follow up of a subject with folate receptor autoantibodies is a first report of its kind and describes treatment strategy to prevent pregnancy related complications due to folate receptor autoantibodies.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Complicaciones del Embarazo
/
Autoanticuerpos
/
Receptor 1 de Folato
Límite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Birth Defects Res A Clin Mol Teratol
Año:
2015
Tipo del documento:
Article