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Synthetic, structural mimetics of the ß-hairpin flap of HIV-1 protease inhibit enzyme function.
Chauhan, Jay; Chen, Shen-En; Fenstermacher, Katherine J; Naser-Tavakolian, Aurash; Reingewertz, Tali; Salmo, Rosene; Lee, Christian; Williams, Emori; Raje, Mithun; Sundberg, Eric; DeStefano, Jeffrey J; Freire, Ernesto; Fletcher, Steven.
Afiliación
  • Chauhan J; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine St., Baltimore, MD 21201, USA.
  • Chen SE; Department of Biology, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.
  • Fenstermacher KJ; Department of Cell Biology & Molecular Genetics, University of Maryland, College Park, MD 20742, USA.
  • Naser-Tavakolian A; Department of Biology, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.
  • Reingewertz T; Department of Microbiology and Immunology, University of Maryland School of Medicine, 725 West Lombard St., Baltimore, MD 21201, USA.
  • Salmo R; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine St., Baltimore, MD 21201, USA.
  • Lee C; PharmD Program, University of Maryland School of Pharmacy, 20 N. Pine St., Baltimore, MD 21201, USA.
  • Williams E; Vivien T Thomas Medical Arts Academy, 100 N Calhoun St., Baltimore, MD 21223, USA.
  • Raje M; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine St., Baltimore, MD 21201, USA.
  • Sundberg E; Department of Microbiology and Immunology, University of Maryland School of Medicine, 725 West Lombard St., Baltimore, MD 21201, USA.
  • DeStefano JJ; Department of Cell Biology & Molecular Genetics, University of Maryland, College Park, MD 20742, USA.
  • Freire E; Department of Biology, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.
  • Fletcher S; Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine St., Baltimore, MD 21201, USA; University of Maryland Greenebaum Cancer Center, 22 S. Greene St., Baltimore, MD 21201, USA. Electronic address: sfletcher@rx.umaryland.edu.
Bioorg Med Chem ; 23(21): 7095-109, 2015 Nov 01.
Article en En | MEDLINE | ID: mdl-26474665
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteasa del VIH / Inhibidores de la Proteasa del VIH / Bibliotecas de Moléculas Pequeñas Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteasa del VIH / Inhibidores de la Proteasa del VIH / Bibliotecas de Moléculas Pequeñas Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos