Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.

Port, Sarah A; Monecke, Thomas; Dickmanns, Achim; Spillner, Christiane; Hofele, Romina; Urlaub, Henning; Ficner, Ralf; Kehlenbach, Ralph H

Port, Sarah A; Monecke, Thomas; Dickmanns, Achim; Spillner, Christiane; Hofele, Romina; Urlaub, Henning; Ficner, Ralf; Kehlenbach, Ralph H.

Afiliación

Port SA; Department of Molecular Biology, Faculty of Medicine, GZMB, Georg-August-University Göttingen, Humboldtallee 23, 37073 Göttingen, Germany.
Monecke T; Department of Molecular Structural Biology, Institute for Microbiology and Genetics, GZMB, Georg-August-University Göttingen, Justus-von-Liebig-Weg 11, 37077 Göttingen, Germany.
Dickmanns A; Department of Molecular Structural Biology, Institute for Microbiology and Genetics, GZMB, Georg-August-University Göttingen, Justus-von-Liebig-Weg 11, 37077 Göttingen, Germany.
Spillner C; Department of Molecular Biology, Faculty of Medicine, GZMB, Georg-August-University Göttingen, Humboldtallee 23, 37073 Göttingen, Germany.
Hofele R; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany; Bioanalytics, Institute for Clinical Chemistry, University Medical Center, Robert-Koch-Str. 40, 37075 Göttingen, Germany.
Urlaub H; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany; Bioanalytics, Institute for Clinical Chemistry, University Medical Center, Robert-Koch-Str. 40, 37075 Göttingen, Germany.
Ficner R; Department of Molecular Structural Biology, Institute for Microbiology and Genetics, GZMB, Georg-August-University Göttingen, Justus-von-Liebig-Weg 11, 37077 Göttingen, Germany. Electronic address: rficner@uni-goettingen.de.
Kehlenbach RH; Department of Molecular Biology, Faculty of Medicine, GZMB, Georg-August-University Göttingen, Humboldtallee 23, 37073 Göttingen, Germany. Electronic address: rkehlen@gwdg.de.

Cell Rep ; 13(4): 690-702, 2015 Oct 27.

Article en En | MEDLINE | ID: mdl-26489467

Asunto(s)

Transporte Activo de Núcleo Celular/fisiología; Núcleo Celular/metabolismo; Carioferinas/metabolismo; Proteínas de Complejo Poro Nuclear/metabolismo; Receptores Citoplasmáticos y Nucleares/metabolismo; Transporte Activo de Núcleo Celular/genética; Sitios de Unión/genética; Sitios de Unión/fisiología; Transporte Biológico/genética; Transporte Biológico/fisiología; Núcleo Celular/química; Cristalografía por Rayos X; Humanos; Carioferinas/química; Proteínas de Complejo Poro Nuclear/química; Unión Proteica; Estructura Terciaria de Proteína; Receptores Citoplasmáticos y Nucleares/química; Proteína Exportina 1

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Núcleo Celular / Receptores Citoplasmáticos y Nucleares / Transporte Activo de Núcleo Celular / Carioferinas / Proteínas de Complejo Poro Nuclear Límite: Humans Idioma: En Revista: Cell Rep Año: 2015 Tipo del documento: Article País de afiliación: Alemania

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