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Synthetic and natural small molecule TLR4 antagonists inhibit motoneuron death in cultures from ALS mouse model.
De Paola, Massimiliano; Sestito, Stefania E; Mariani, Alessandro; Memo, Christian; Fanelli, Roberto; Freschi, Mattia; Bendotti, Caterina; Calabrese, Valentina; Peri, Francesco.
Afiliación
  • De Paola M; Department of Environmental Health Sciences, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via La Masa, 19, Milano, Italy. Electronic address: massimiliano.depaola@marionegri.it.
  • Sestito SE; Department of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza, 2, 20126 Milano, Italy.
  • Mariani A; Department of Environmental Health Sciences, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via La Masa, 19, Milano, Italy.
  • Memo C; Department of Environmental Health Sciences, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via La Masa, 19, Milano, Italy.
  • Fanelli R; Department of Environmental Health Sciences, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via La Masa, 19, Milano, Italy.
  • Freschi M; Department of Neuroscience, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via La Masa, 19, Milano, Italy.
  • Bendotti C; Department of Neuroscience, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Via La Masa, 19, Milano, Italy.
  • Calabrese V; Department of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza, 2, 20126 Milano, Italy.
  • Peri F; Department of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza, 2, 20126 Milano, Italy. Electronic address: francesco.peri@unimib.it.
Pharmacol Res ; 103: 180-7, 2016 Jan.
Article en En | MEDLINE | ID: mdl-26640075
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenoles / Receptor Toll-Like 4 / Aceite de Oliva / Esclerosis Amiotrófica Lateral / Neuronas Motoras Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenoles / Receptor Toll-Like 4 / Aceite de Oliva / Esclerosis Amiotrófica Lateral / Neuronas Motoras Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2016 Tipo del documento: Article