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Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts.
Fasanelli, Francesca; Baglietto, Laura; Ponzi, Erica; Guida, Florence; Campanella, Gianluca; Johansson, Mattias; Grankvist, Kjell; Johansson, Mikael; Assumma, Manuela Bianca; Naccarati, Alessio; Chadeau-Hyam, Marc; Ala, Ugo; Faltus, Christian; Kaaks, Rudolf; Risch, Angela; De Stavola, Bianca; Hodge, Allison; Giles, Graham G; Southey, Melissa C; Relton, Caroline L; Haycock, Philip C; Lund, Eiliv; Polidoro, Silvia; Sandanger, Torkjel M; Severi, Gianluca; Vineis, Paolo.
Afiliación
  • Fasanelli F; Molecular end Epidemiology Unit, HuGeF, Human Genetics Foundation, Torino 10126, Italy.
  • Baglietto L; Unit of Cancer Epidemiology, Citta' della Salute e della Scienza Hospital-University of Turin, Center for Cancer Prevention, Via Santena 7, Torino 10126, Italy.
  • Ponzi E; Inserm (Institut National de la Santé et de la Recherche Médicale), Centre for Research in Epidemiology and Population Health, U1018, Team 9, 114 rue Edouard Vaillant, Villejuif 94805, France.
  • Guida F; Paris-South University, Villejuif 91450, France.
  • Campanella G; Department of Genetic Epidemiology, Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Victoria 3004, Australia.
  • Johansson M; School of Population and Global Health, Centre for Epidemiology and Biostatistics, University of Melbourne, Melbourne, Victoria 3010, Australia.
  • Grankvist K; Molecular end Epidemiology Unit, HuGeF, Human Genetics Foundation, Torino 10126, Italy.
  • Johansson M; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK.
  • Assumma MB; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK.
  • Naccarati A; Genetic Epidemiology Division, International Agency for Research on Cancer, Lyon 69008, France.
  • Chadeau-Hyam M; Department of Biobank Research, Umeå University, Umeå SE-90187, Sweden.
  • Ala U; Department of Biobank Research, Umeå University, Umeå SE-90187, Sweden.
  • Faltus C; Department of Radiation Sciences, Umeå University, Umeå SE-90187, Sweden.
  • Kaaks R; Molecular end Epidemiology Unit, HuGeF, Human Genetics Foundation, Torino 10126, Italy.
  • Risch A; Molecular end Epidemiology Unit, HuGeF, Human Genetics Foundation, Torino 10126, Italy.
  • De Stavola B; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK.
  • Hodge A; Department of Molecular Biotechnology and Health Sciences, Università di Torino, Torino 10126, Italy.
  • Giles GG; Division of Epigenomics and Cancer Risk Factors, DKFZ-German Cancer Research Center, Heidelberg 69121, Germany.
  • Southey MC; Division of Cancer Epidemiology, DKFZ-German Cancer Research Center, Heidelberg 69121, Germany.
  • Relton CL; Translational Lung Research Center Heidelberg, Member of the German Center for Lung Research (DZL), Heidelberg 69120, Germany.
  • Haycock PC; Division of Epigenomics and Cancer Risk Factors, DKFZ-German Cancer Research Center, Heidelberg 69121, Germany.
  • Lund E; Translational Lung Research Center Heidelberg, Member of the German Center for Lung Research (DZL), Heidelberg 69120, Germany.
  • Polidoro S; Division of Cancer Research and Epigenetics, Department of Molecular Biology, University of Salzburg, Salzburg 5020, Austria.
  • Sandanger TM; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
  • Severi G; Department of Genetic Epidemiology, Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Victoria 3004, Australia.
  • Vineis P; Department of Genetic Epidemiology, Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Victoria 3004, Australia.
Nat Commun ; 6: 10192, 2015 Dec 15.
Article en En | MEDLINE | ID: mdl-26667048

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fumar / Regulación de la Expresión Génica / Predisposición Genética a la Enfermedad / Neoplasias Pulmonares Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fumar / Regulación de la Expresión Génica / Predisposición Genética a la Enfermedad / Neoplasias Pulmonares Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2015 Tipo del documento: Article País de afiliación: Italia