Sweating: A Specific Predictor of ST-Segment Elevation Myocardial Infarction Among the Symptoms of Acute Coronary Syndrome: Sweating In Myocardial Infarction (SWIMI) Study Group.
Clin Cardiol
; 39(2): 90-5, 2016 Feb.
Article
en En
| MEDLINE
| ID: mdl-26695479
ABSTRACT
BACKGROUND:
Today, cardiologists seek to minimize time from symptom onset to interventional treatment for the most favorable results.HYPOTHESIS:
In the acute coronary syndrome (ACS) symptom complex, sweating can differentiate ST-segment elevation myocardial infarction (STEMI) from non-ST-segment elevation ACS (NSTE-ACS) during early hours of infarction.METHODS:
This single-center, prospective, observational study compared symptoms of STEMI and NSTE-ACS patients admitted from August 2012 to July 2014.RESULTS:
Of 12 913 patients, 90.56% met ACS criteria. Among these, 22.51% had STEMI. Typical angina was the most common symptom (83.82%). On stepwise multiple regression, sweating (odds ratio 97.06, 95% confidence interval [CI] 82.16-114.14, P < 0.0001) and typical angina (odds ratio 2.72, 95% CI 2.18-3.38, P < 0.001) had significant association with STEMI. For diagnosis of STEMI, positive likelihood ratio (LR) and positive predictive value (PPV) were highest for typical angina with sweating (LR 11.17, 95% CI 10.31-12.1; PPV 76.09, 95% CI 74.37-77.75), followed by sweating with atypical angina (LR 3.6, 95% CI 3.07-4.21; PPV 50.61, 95% CI 46.45-54.76), typical angina (LR 1.05, 95% CI 1.03-1.07; PPV 22.97, 95% CI 22.11-23.84), and atypical angina (LR 0.77, 95% CI 0.69-0.87; PPV 18.09, 95% CI 16.32-19.97). C statistic values of 0.859 for typical angina with sweating and 0.519 for typical angina alone reflected high discriminatory value of sweating for STEMI prediction.CONCLUSIONS:
Presence of sweating with ACS symptoms predicts probability of STEMI, even before clinical confirmation. Sweating in association with typical or atypical angina is a much better predictor of STEMI than NSTE-ACS.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sudoración
/
Síndrome Coronario Agudo
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Infarto del Miocardio
Tipo de estudio:
Diagnostic_studies
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Etiology_studies
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
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Aged80
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Clin Cardiol
Año:
2016
Tipo del documento:
Article
País de afiliación:
India